Meigs' malady and adult-type granulosa cellular cancer.

With 50% ethanol solution, the DNA conformational transition passes through two steps (i) fast and constant-velocity contraction and (ii) relatively slow contraction from the free end. The first process is attributed to the B to A conformational transition by gradual dehydration. The second process is due to the coil-globule transition as the free end of DNA starts the contraction. This globular structure formation counteracts the shear force from the microfluids and decelerates the contraction velocity. This real-time observation system can be applied to the kinetic analysis of DNA conformational transitions such as kinetics of chromatin assembly and gene expression.Developing a noncontact ratiometric luminescent temperature sensor with high sensitivity, widely available emission range, and reliable performance is a challenge in materials science. Herein, we demonstrated that this goal can be achieved by fabricating a lanthanide-functionalized hydrogen-bonded organic framework film (named the Eu@HOF-TCBP film). The unbonded carboxylic groups that existed in the structure not only enable lanthanide ions to bind with the framework for bringing dual emission but also allow for preparing a hydrogen-bonded organic framework (HOF) film through the facile electrophoretic deposition. The obtained film exhibits ratiometric temperature sensing performance in the range of 297-377 K with a maximum relative sensitivity of 5.787% K-1 and shows repeated use without sensitivity loss. Moreover, the material can be easily recycled and refabricated with consistent performance, demonstrating its unique merits of easy recyclability and regeneration as an HOF material. We believe that the reported strategies for preparing a dual-emitting HOF and fabricating a thin film will open a window for HOF applications.We have developed a protocol to facilitate the nickel-catalyzed decarbonyloxidation of 3-aryl benzofuran-2(3H)-ones to 2-hydroxybenzophenones under mild conditions, which is an efficient approach for the decarbonyloxidation of lactones in organic synthesis. A diverse range of substrates can undergo C(O)-O/C(O)-C bond cleavage to generate the target products in good yields. These 2-hydroxybenzophenones can be converted into a variety of compounds via reactions such as esterification, cyclization, and reduction.Aim To determine factors associated with overweight/obesity in preschool children. Methods This cross-sectional study was carried out in paediatric outpatient departments of the Public Institution Primary Health Care Centre of Canton Sarajevo, Bosnia and Herzegovina. The study included 300 preschool children who were divided into two groups normal weight (n=150) and overweight/obese (n=150). Children were weighed and measured and body mass index was calculated. Data concerning potential childhood overweight/obesity risk factors (sociodemographic characteristics of child and mother, physical activity and sedentary behaviour of the child) were collected using a designed questionnaire filled in by the mothers. Logistic regression analysis was used to estimate the association between potential risk factors and overweight/obesity in preschool children. Results Male gender of the children (p=0.043) and maternal overweight (p=0.000) were positively associated with child overweight/obesity. Male children were 1.6 times more likely to be overweight/obese than female (95% CI 1.01-2.53). Children of overweight mothers were 3.34 times more likely to be overweight/ obese than children with mothers of normal weight (95% CI 1.77- 6.28). Physical activity 180 minutes/day (p=0.020), regular snacking while watching television, using computer/tablet/ mobile phones (p=0.000) were associated with overweight/obesity status of the preschool children. Conclusion Public health programs that aim to reduce overweight/ obesity in preschool children should mainly help mothers understand the serious risk of childhood obesity and the importance of them creating a healthy lifestyle in childhood.Aim To compare maternal, foetal and neonatal characteristics, and perinatal outcome of preterm and term deliveries in twins pregnancies in order to improve perinatal care in Bosnia and Herzegovina. Methods This retrospective cohort study included pregnant women with twin pregnancy who delivered during the period between 1 January 2012 and 31 December 2018 at the Clinic for Gynaecology and Obstetrics, University Clinical Centre Tuzla. Results During the seven-year period 26 734 deliveries were recorded, out of which 362 (1.35 %) were twin pregnancies, 226 (62.4%) preterm and 136 (37.5%) term ones. In the preterm group 38 (16.8%) pregnancies were assisted medical reproduction, and 16 (11.7%) of those were in the term group. The average birth weight was significantly higher for the first twin in both groups (p less then 0.00001). Incipient intrauterine foetal asphyxia was more frequent in the preterm group (p less then 0.05). The most common indication for Caesarean section was abnormalities of foetal presentation and lie, 176 (68.2%) for the overall sample. Conclusion Cornerstone of twin pregnancy antenatal care is to get correct data about amnionicity and chorionicity. Since majority of prenatal data did not have this information we call all obstetricians to declare about amnionicity and chorionicity in twin pregnancies during the first trimester ultrasound examination.Aim To determine the degree of accuracy in determining the sex of the skull based on classical morphometric analysis of the mastoid process. Morphometric analysis excluded a subjective approach expressed in osteoscopic analysis. Methods The study was conducted on a sample of 100 macerated skulls of known gender and age from the second half of the 20th century, including the Bosnian population. Of the 100 skulls, 50 (50%) were male and 50 (50%) were female. Male skulls were on average 60 (47-71) years old and female 57 (43-76) years old. VcMMAE solubility dmso At each mastoid process, 3 measurements were made mastoid length, mastoid width (medio-lateral diameter) ML) and anteroposterior diameter (AP) of the mastoid process. Results Using the univariate method, we found a significant difference between length, width, AP diameter and size of mastoid processes as well as between gender (p less then 0.05). Multivariate binary logistic regression showed statistically significant differences in AP diameter of the mastoid process (p less then 0.VcMMAE solubility dmso