description of levels of evidence.
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.Background The predictive validity of components of the Graduate Record Examination (GRE) on student success is inconsistent, and the test itself has been shown to be a barrier for prospective students historically underrepresented in graduate programs. Policy Options and Recommendations We analyzed three admissions cycles for the Master of Public Health degree at the Boston University School of Public Health before (2016, 2017, 2018) and after (2019, 2020, 2021) eliminating the GRE for diversity and quality of applications, student success, and employment outcomes. We observed increases in diversity (e.g., 7.1% and 7.0% self-identified as African American/Black and Hispanic before eliminating the GRE as compared to 8.5% and 8.2% after), but no loss of quality, as measured by undergraduate grade point averages (GPAs) (e.g., median undergraduate GPA before and after eliminating the GRE of 3.4). We also saw no difference in performance in required core courses (e.g., more than 93.5% of students earned passing grades in required courses before and 94.5% after eliminating the GRE) and graduate employment (i.e., 93.1% employed within 6 months of graduation before and 93.8% after eliminating the GRE). We recommend removing the GRE as an admission requirement for the MPH as a step toward diversifying the public health workforce. This change alone is necessary but insufficient. We also need to develop support programs, tailored specifically to the needs of our future students, to ensure their success. Conclusion Eliminating the GRE as an admissions requirement for prospective students does not result in loss of student quality or worse program performance.A 50-year old healthy male lost control over the pull string of a milling machine, which strangulated his right elbow and forearm with high velocity. Magnetic resonance imaging of the right upper extremity revealed a substantial tear in the muscle belly of the musculus brachioradialis with multiple small defects in the surrounding musculature of the forearm. The affected arm was immobilized for 1 week with an above the elbow cast. In the following months, guided training and strengthening exercises were performed. The patient could return to his physically demanding work after 10 months and regained full function of his hand and wrist after 18 months. This case report demonstrates that short immobilization followed by extensive and guided strength training has been observed to result in persisting weakness of elbow flexion but good functional outcome for the wrist and hand.Fresh cassava roots that contain hydrocyanic acid (HCN) can be hazardous to animals when consumed. Prior literature has shown that adding sulfur may eliminate HCN without harming the health of animals. Additionally, adding urea is advised if sulfur was utilized since it helps with microbial protein synthesis. We thus proposed that supplementing the fresh cassava root diet with a high sulfur and urea in concentrate diet would be advantageous for rumen fermentation and milk production in animals. The purpose of this study was to see how high sulfur and urea levels in concentrate combinations affected feed utilization, rumen fermentation, and milk production in dairy cows fed diets including fresh cassava root. Four Holstein Friesian cows with 480 ± 50.0 kg BW, 10 ± 2 kg/head/day of milk yield, and 90 days in milk (DIM) were assigned at random in a 4 × 4 Latin square design with a 2 × 2 factorial design. Factor A was the concentration of sulfur in the concentrate diet at 10 g/kg and 20 g/kg dry matter (DM), while factor B was the concentration of urea in the concentrate diet at 10 g/kg and 20 g/kg DM. Fresh cassava root was given to each cow on a daily basis at a rate of 15 g DM/kg of BW. According to the findings, sulfur and urea had no interaction impact on feed intake, rumen fermentation, or milk production. Sulfur supplementation at 20 g/kg DM improved sulfur intake and digestibility of DM and organic matter much more than 10 g/kg sulfur. Additionally, sulfur supplementation at a dose of 20 g/kg DM in concentrate markedly increased blood and milk thiocyanate concentrations while lowering the somatic cell count. When compared to 10 g/kg DM urea, 20 g/kg DM urea significantly enhanced crude protein digestibility, ammonia-nitrogen concentration, blood urea nitrogen, and total volatile fatty acid concentration. Sulfur might detoxify hydrogen cyanide toxicity and be added at 20 g/kg DM in concentrate without harming the animals, whereas urea at 20 g/kg DM could increase feed digestion and rumen fermentation.Contagious caprine pleuropneumonia (CCPP) is a highly fatal infectious disease of goats, caused by Mycoplasma capricolum subsp. capripneumoniae (Mccp). This disease is causing huge economic losses to the goat industry in Pakistan. However, little is known about the epidemiology of CCPP, especially in the hard areas of Khyber Pakhtunkhwa (KP), Pakistan, despite having a huge population of goats. Therefore, this study aimed to elucidate sero-molecular epidemiology and pathology associated with Mccp infection in goats in southern areas of KP including Dera Ismail Khan (DI Khan), Bannu, Karak, and Kohat. A total of 200 (50 from each area) serum samples were collected from clinically infected goats, whereas 600 various samples (nasal swab n = 50, pleural fluid n = 50, lungs n = 50 at each selected area of study) were collected from live goats showing respiratory clinical signs and dead/slaughter goats having lesions in the lungs/pleura. A commercial competitive ELISA kit confirmed anti-Mccp antibodies in altogethe Mccp was found in serum samples collected from Kohat by ELISA.
Patients with mucosal lesions form a significant number of routine outpatients presenting to the dermatology department where diagnostic confirmation using histopathological examination of mucosal biopsy is neither feasible nor warranted in every patient.
To study the dermoscopic features of various mucosal lesions affecting the oral cavity and to assess the reliability of mucoscopy vis-a-vis clinico-laboratory findings.
An observational, cross-sectional, hospital-based study was conducted over a period of 2 years from March 2019 to February 2021 in the dermatology outpatient department. Patients presenting with oral mucosal lesions, with or without associated cutaneous involvement, were recruited for mucoscopic evaluation after taking an informed written consent. A detailed history and clinical examination, with emphasis on mucocutaneous examination, was performed and findings were recorded on a standard predesigned proforma. Mucoscopy of oral mucosa was carried out using a handheld dermoscope as well ous mucocutaneous disorders. Mucoscopy could be a helpful aid in diagnosing pigmented skin lesions and alleviating the apprehension regarding oral melanoma and serve as a screening tool in case of squamous cell carcinoma lips.
Confirmatory histopathological analysis and correlation with mucoscopic findings could not be established in our study.
Confirmatory histopathological analysis and correlation with mucoscopic findings could not be established in our study.
Presently the leprosy program has no defined surveillance protocols for patients who complete the fixed duration multidrug therapy and are released from treatment (RFT). Hence, the information about the post-RFT events in these patients is sparse and qualitative and quantitative data regarding their health care requirements is missing. During the
survey carried out by the Indian Association of Dermatologists,Venereologists and Leprologists (IADVL), a number of patients presented to dermatologists during the post RFT period for a variety of symptoms. This paper analyses the events in these patients during the post RFT period.
Out of a total of 3701 leprosy patients who presented to 201 dermatologists across India during the
survey, 708 (26.2%) were in the post RFT period (488 males; 220 females). Of these, 21% were PB and 79% MB patients as per their treatment records. Majority were in the age group of 31-59 years (55.5%); however, a significant proportion of them (20.7%) were elderly (>60 years).lated social issues.
The DermLep Survey highlights the importance of 'post RFT' patients as an important subset of leprosy patients who visit dermatologists for various health related issues. The most common complaints in this subset were active/persistent skin lesions, lepra reactions and neuritis. In these patients, who are a sub-group of 'persons affected with leprosy' the disease related issues can persist for many years post RFT. Hence, it is important to provide services in the programme to monitor and manage these complications for the prevention of impairments, disability and the related social issues.
Various nail manifestations have been reported with COVID-19; mostly in the form of isolated reports.
This cross-sectional study was carried out to assess nail changes in hospitalized patients with moderate to severe COVID-19.
Nail findings in 43 adults being treated for COVID-19, were evaluated after obtaining informed written consent. Nail changes involving fingernails and toenails were documented as new-onset or pre-existing changes. Disease status, hematological and biochemical tests, inflammatory markers, treatment administered and outcomes were also recorded. The frequency of changes in fingernails and toenails were statistically compared.
The red half-moon sign (32.5%) and nail bed erythema (34.8%) were the commonest changes seen in fingernails; while apparent leukonychia (46.5%) and distal brown discoloration (51.1%) were commonest changes in toenails. The difference in frequency of changes seen between fingernails and toenails was statistically significant (p < 0.05). Nail changes correlated with systemic involvement in these patients.
Single-center evaluation in a limited number of patients, without using augmented examination techniques like onychoscopy, nail fold capillaroscopy, or fluoroscence. Those with less severe disease or with rapid fatality could not be studied.
Nail changes in COVID-19 are common and reflect the systemic nature of illness, being a harbinger of underlying complications.
Nail changes in COVID-19 are common and reflect the systemic nature of illness, being a harbinger of underlying complications.
Skin disorders represent a major proportion of occupational disorders. Dermatoses are becoming a source of concern in various population groups. In Kashmir valley, a large number of people are associated directly or indirectly with horticulture. selleck chemical Fruit cultivation is the main occupation of around 33 lakh people in the Union Territory.
To study the profile of dermatological disorders in workers involved in fruit growing industry of Kashmir valley.
This study was a cross-sectional observational study, carried out over a period of 2 years, in which 701 workers of fruit growing industry of Kashmir valley were screened.
276 (39.37%) of these workers were found to have skin lesions while the rest, that is, 425 (60.63%) were not found to have any dermatoses. Out of the total dermatological lesions observed, occupational dermatoses contributed to 94 cases (34.05%), while non-occupational dermatoses accounted for 182 cases (65.94%). Among the occupational dermatoses, friction-related disorders (callosities and cuts) were predominant (15.selleck chemical
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