In the field of assisted reproductive technology (ART), particularly in vitro fertilisation (IVF), precision and care are of paramount importance. Among the myriad tools used in IVF procedures, denudation pipettes play a crucial role in ensuring the success of various steps, from oocyte preparation to embryo transfer. This article explores the significance, design, and applications of denudation pipettes in IVF.
What Are Denudation Pipettes?
Denudation pipettes are specialised laboratory instruments designed for handling and manipulating oocytes during the IVF process. They are thin, cylindrical tools with precisely controlled diameters, used primarily to remove the cumulus cells surrounding the oocyte. This process, known as denudation, is essential for assessing the maturity of the oocyte and preparing it for subsequent fertilisation steps.
Cryolab Denudation Product Range
Cryolab Denudation Pipettes – Straight Cut – Cryolab
Specialised tools for the precise removal of the outer layer surrounding an embryo during assisted reproductive procedures. These straight-cut micropipettes are available in a range of inner diameters (125μm to 300μm) to accommodate various embryo sizes and stages of development. Their ergonomic design ensures precise handling and minimal disruption to embryo integrity during denudation.
Cryolab ICSI Pipettes – Angled Cut – Cryolab
Meticulously designed for intracytoplasmic sperm injection (ICSI) procedures, enabling precise injection of a single sperm into an egg. These pipettes have inner diameters ranging from 4 to 6μm, bend angles from 0° to 35°, and bevel lengths from 11 to 20μm, ensuring optimal control and accuracy during ICSI manipulations. The angled cut provides an ideal orientation for smooth sperm delivery and reduced handling time.
Cryolab Holding Pipettes – Straight Cut – Cryolab
Specialised tools designed for securely holding embryos during various micromanipulation procedures, including biopsy and assisted hatching. These straight-cut pipettes are available with inner diameters ranging from 15 to 30μm and bend angles from 0° to 35°, providing flexibility and precision in embryo handling. Their robust design allows for steady immobilisation of embryos, critical for success in advanced ART procedures.
Cryolab Biopsy Micropipettes – Straight Cut – Cryolab
Specialised tools used for extracting small samples of cells from an embryo during preimplantation genetic testing procedures. These pipettes feature straight cuts with inner diameters from 20 to 40μm and bend angles from 20° to 35°. The carefully controlled dimensions ensure efficient and gentle cell sampling without compromising the embryo’s viability.
Applications of Cryolab Pipettes
Cryolab micropipettes are widely used across ART for various critical steps, including:
Denudation: Preparing oocytes for fertilisation by removing cumulus cells.
ICSI: Directly injecting a single sperm into the oocyte to facilitate fertilisation.
Embryo Holding: Stabilising embryos during procedures such as assisted hatching and genetic biopsies.
Biopsy: Extracting cells for preimplantation genetic diagnosis or screening.
Additional Features of Cryolab Pipettes
Durable Glass Construction: High-quality borosilicate glass ensures precision, durability, and biocompatibility.
Ergonomic Handling: Designed for use with micro-manipulators to ensure ease of operation and maximum control.
Consistent Performance: Each pipette is rigorously tested to meet industry standards, ensuring reliability in sensitive ART procedures.
[Why Cryolab Pipettes?
Cryolab’s commitment to quality ensures that IVF specialists and laboratories have access to the best products for their work. With a comprehensive range of pipettes suited for different ART applications, Cryolab continues to support advancements in fertility treatment. Our products are trusted by professionals worldwide for their precision, reliability, and exceptional design.
Contact Us
For more information about our cryogenic products or to place an order, please email us at info@cryolab.co.uk or visit www.cryolab.co.uk. We are committed to providing cryo products that empower healthcare professionals and laboratories to achieve success in assisted reproduction.](https://cryolab.co.uk/)
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