With the advancements in technology, dental pedagogy has also evolved, and new learning technologies have emerged. Virtual reality (VR) as an education tool in dentistry is underutilised. VR as an adjunct in local anaesthesia (LA) teaching in paediatric dentistry has not been investigated. The study aimed to investigate dental student's perception of dental LA VR simulation on a paediatric patient and to determine whether this can improve students learning experience.
Seventy-one students participated in a self-administered questionnaire before and after the use of dental LA VR simulator. Descriptive analysis was performed to determine the perceptions of experience gained through VR. The data were tabulated, graphed, and analysed using SPSS and GraphPad Prism software.
The study noted that 89.9% of participants perceived that it would improve their LA skills. After using dental LA VR, 83.1% of participants experienced more engaged in the learning activity, and 55.0% of participants agreed/strongly agreed that it improved their understanding of anatomical landmarks. Around 56.4% of participants agreed/strongly agreed that it added value compared with traditional LA teaching methods.
It can be concluded that the use of VR simulation can enhance students engagement and learning experience in paediatric dentistry settings and can be used as an additional means of LA training.
It can be concluded that the use of VR simulation can enhance students engagement and learning experience in paediatric dentistry settings and can be used as an additional means of LA training.
To compare the color stability of a microhybrid and two nanocomposites after exposure to common soft drinks among adolescents.
Ninety discs were prepared from a microhybrid (Filtek Z250) and two nanocomposites (Filtek Z350 and Tetric N-Ceram) (n = 30 each). Six discs from each material were then immersed in one of five drinks (iced tea, sports drink, orange juice, cola, and distilled water) for 15days. Color measurement was performed at baseline and after 15days using a spectrophotometer according to the CIE L*a*b* system, and the change in color values as well as total color change (ΔE) was calculated and compared. ANOVA and Tukey's HSD test were used to analyze the data (p < 0.05).
Significant change in color values and total color (ΔE > 3.3) was observed in the composite materials after immersion in the soft drinks compared to immersion in distilled water (ΔE < 3.3). The highest mean values were those of Filtek Z350, being significantly different from the rest of the materials. Independent of the composite material, iced tea resulted in the highest mean values, being significantly different from the rest of the drinks (p < 0.05).
All soft drinks resulted in clinically unacceptable discoloration of the composite materials with maximum discoloration being that following immersion of composite materials, particularly Filtek Z350, in iced tea. Consequently, in dental practice, adolescents should be asked about their consumption of soft drinks, particularly iced tea, and made aware of their potential to discolor composite restorations if they are to receive them.
All soft drinks resulted in clinically unacceptable discoloration of the composite materials with maximum discoloration being that following immersion of composite materials, particularly Filtek Z350, in iced tea. Consequently, in dental practice, adolescents should be asked about their consumption of soft drinks, particularly iced tea, and made aware of their potential to discolor composite restorations if they are to receive them.Mitochondria are vital cellular organelles associated with energy production as well as cell signaling pathways. These organelles, responsible for metabolism, are highly abundant in hepatocytes that make them key players in hepatotoxicity. ALK inhibitor review The literature suggests that mitochondria are targeted by various environmental pollutants. Arsenic, a toxic metalloid known as an environmental pollutant, readily contaminates drinking water and exerts toxic effects. It is toxic to various cellular organs; among them, the liver seems to be most affected. A growing body of evidence suggests that within cells, arsenic is highly toxic to mitochondria and reported to cause oxidative stress and alter an array of signaling pathways and functions. Hence, it is imperative to highlight the mechanisms associated with altered mitochondrial functions and integrity in arsenic-induced liver toxicity. This review provides the details of mechanistic aspects of mitochondrial dysfunction in arsenic-induced hepatotoxicity as well as various ameliorative measures undertaken concerning mitochondrial functions.Organophosphate compounds are the most widely employed insecticides in countries with high agriculture activity. On average, organophosphates cause 3 million people to poison and 200 000 deaths per year due to food chain or occupational, accidental, or suicidal exposure. Our study aimed to research selenium's protective role against the toxic action of CPF, one of the most commonly used organophosphates, with an experimental model formed with rats. A total of 56 male SD rats were distributed into seven groups as follows control (tap water), sham (corn oil), group I (5.4 mg/kg CPF), group II (13.5 mg/kg CPF), group III (3 mg/kg Se), group IV (5.4 mg/kg CPF+Se), and group V (13.5 mg/kg CPF+Se). Following 6 weeks of oral exposure, there were significant changes in AChE activity, biochemical and hematological parameters, and trace element levels in CPF-treated rats. In the high-dose CPF group, RBC values, Hb, and Hct decreased, and values of WBC, AST, ALT, ALP increased (p less then 0.001) significantly compared to control, sham, and Se groups. While there was no significant change in zinc level, the copper and selenium levels were significantly higher in group IV than in control (p less then 0.001) and sham (p less then 0.05, p less then 0.01, respectively) groups. Moreover, max. O.R.L. was found statistically more elevated in the high-dose CPF group compared to control, sham, and Se groups (p less then 0.05, p less then 0.05, and p less then 0.01, respectively). All results indicated that Se is an antioxidant that reduces the toxic effects caused by CPF. Employing combinations of chlorpyrifos and selenium appeared greatly in restoring the harmful effects of CPF exposure.ALK inhibitor review
Top comments (0)