Finally, the knowledge gaps and opportunities in CaO2-based sludge treatment technologies that need to be focused in the future are prospected. The review presented can supply a theoretical basis and technical reference for the application of CaO2 for improving the treatment of WAS.Fe(III)-loaded chitosan (CTS-Fe) composite was used for the first time to remove and recover phosphorus (P) from waste activated sludge (WAS) via anaerobic digestion (AD). saruparib The P transformation pathway and the effect of CTS-Fe addition on the AD process were investigated using batch experiments. The P fractionation results indicate that non-apatite inorganic phosphorus (NAIP) reduction in the solid phase of sludge at 20 g/L of CTS-Fe addition (6.72 mg/g-SS) was 2.4 times higher than that in the control (2.77 mg/g-SS, no CTS-Fe addition). This is probably brought about by the added CTS-Fe enhanced the reduction of Fe(III)-P compounds in the sludge with phosphate released into the liquid phase. CTS-Fe can efficiently recover 95% of P from the liquid digestate of WAS. Notably, partial Fe(III) on the CTS-Fe was reduced and effectively combined with P to form vivianite crystals on the CTS-Fe surface during the AD process. Characterization analysis demonstrated that ligand exchange and chemical precipitation were the dominant mechanisms for P removal/recovery. Furthermore, the addition of CTS-Fe increased methane production by 11.9 - 32.2% under the tested conditions, likely attributable to the enhanced hydrolysis of WAS under CTS-Fe supplementation. As the P-loaded CTS-Fe particles can be easily separated and recovered from the AD system and further reutilized in agriculture, this study could provide a new approach for simultaneous P removal/recovery and enhanced methane production from AD of WAS.Microplastic (MP) pollution is an increasing global problem due to the ubiquity of these particles in the environment and the uncertainty surrounding their fate. Most MPs undergo extensive weathering in the environment, which may result in the release of dissolved organic matter (DOM) into the aqueous phase. In this study, for the first time, we examined the adsorptive behavior of MP-derived DOM (MP-DOM) on minerals (kaolinite and goethite) using DOM samples leached from commercial plastics including polyvinylchloride (PVC) and polystyrene (PS) under dark and ultraviolet (UV) irradiation conditions. MP-DOM was characterized by a higher distribution of relatively smaller-sized molecules than natural organic matter (NOM). The PS-derived DOM (PS-DOM) leached under UV treatment exhibited more oxygen-containing groups than their counterparts in the dark. MP-DOM also exhibited net negative charges at neutral pH ranges. Adsorption isotherm experiments revealed that the mineral surfaces had high adsorption affinitiesonmental impacts of MPs.
To investigate cerebral blood flow (CBF) characteristics before and after hemodialysis initiation and their longitudinal associations with global cognitive function in older adults.
A cohort of 17 older end-stage renal disease patients anticipating standard thrice-weekly hemodialysis and a group of 11 age- and sex-matched healthy control volunteers were recruited for brain perfusion imaging studies using arterial spin labeling. Hemodialysis patients participated in a prospective longitudinal study using brain magnetic resonance imaging and global cognitive assessment using the Modified Mini-Mental State Examination (3MS) at two time points baseline, 2.9±0.9months before, and follow-up, 6.4±2.4months after hemodialysis initiation. Healthy controls were imaged once using the same protocol. CBF analyses were performed globally in grey and white matter and regionally in the hippocampus and orbitofrontal cortex. Covariate-adjusted linear mixed-effects models were used for statistical analyses (significance p&lsociation between longitudinal changes in regional CBF and 3MS scores suggest that decreased brain perfusion may contribute to the observed cognitive decline.
Insomnia disorder has been reclassified into short-term/acute and chronic subtypes based on recent etiological advances. However, understanding the similarities and differences in the neural mechanisms underlying the two subtypes and accurately predicting the sleep quality remain challenging.
Using 29 short-term/acute insomnia participants and 44 chronic insomnia participants, we used whole-brain regional functional connectivity strength to predict unseen individuals' Pittsburgh sleep quality index (PSQI), applying the multivariate relevance vector regression method. Evaluated using both leave-one-out and 10-fold cross-validation, the pattern of whole-brain regional functional connectivity strength significantly predicted an unseen individual's PSQI in both datasets.
There were both similarities and differences in the regions that contributed the most to PSQI prediction between the two groups. Further functional connectivity analysis suggested that between-network connectivity was re-organized between short-term/acute insomnia and chronic insomnia.
The present study may have clinical value by informing the prediction of sleep quality and providing novel insights into the neural basis underlying the heterogeneity of insomnia.
The present study may have clinical value by informing the prediction of sleep quality and providing novel insights into the neural basis underlying the heterogeneity of insomnia.Brain plasticity potential is a central theme in neuro-oncology and is currently receiving increased attention. Advances in treatment have prolonged life expectancy in neuro-oncological patients and the long-term preservation of their quality of life is, therefore, a new challenge. To this end, a better understanding of brain plasticity mechanisms is vital as it can help prevent permanent deficits following neurosurgery. Indeed, reorganization processes can be fundamental to prevent or recover neurological and cognitive deficits by reallocating brain functions outside the lesioned areas. According to more recent studies in the literature, brain reorganization taking place following neurosurgery is associated with good neurofunctioning at follow-up. Interestingly, in the last few years, the number of reports on plasticity has notably increased. Aim of the current review was to provide a comprehensive overview of pre- and postoperative neuroplasticity patterns. Within this framework, we aimed to shed light on some tricky issues, including i) involvement of the contralateral healthy hemisphere, ii) role and potential changes of white matter and connectivity patterns, and iii) reorganization in low- versus high-grade gliomas.saruparib
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