e conducive to the restoration of alveolar bone mineral density in the upper incisor than the conventional lip-side fixed appliance, and both of which have the same effect on bone height and are safe and effective orthodontic treatment.
To compare the reliability of digital model and plaster model on evaluation of bilateral cleft lip and palate.
Nineteen pairs of digital and plaster model obtained from bilateral cleft lip and palate patients were measured, including nine measurements, such as maxillary alveolar length, width, cleft width, the deviation of maxillary middle line. https://www.selleckchem.com/products/gsk805.html One-way ANOVA was conducted for statistical analysis with SPSS 24.0 software package.
There was no significant difference between the repeated measurements of the two types of models, there was no significant difference in the measurements between two types of models used in clinic.
Both methods are suitable for evaluation of bilateral cleft lip and palate patients. Compared with conventional plaster model, digital model provides a safer and convenient way to obtain useful information both for research and clinical need.
Both methods are suitable for evaluation of bilateral cleft lip and palate patients. Compared with conventional plaster model, digital model provides a safer and convenient way to obtain useful information both for research and clinical need.
To investigate the expression of metalloproteinase-14 (MMP-14), growth inhibitory factor 4 (ING4) and hypoxia-inducible factor-1α (HIF-1α) in human oral squamous cell carcinoma (OSCC) and their clinical significance, to provide references for clinical diagnosis and treatment of OSCC.
Sixty patients with OSCC admitted to our hospital from July 2014 to July 2019 were enrolled in this study. The tissue specimen of 60 patients were prepared into paraffin sections as the experimental group, while 20 cases of normal oral mucosal tissue were paraffin-embedded as the control group. Immunohistochemical S-P method was used to analyze the positive expression levels of MMP-14, ING4 and HIF-1α in oral mucosa of the two groups. The relationship between the 3 indicators and the different clinicopathological features of OSCC patients was analyzed, the correlation of the expression level between 3 protein was also calculated. SPSS 23.0 software package was used for statistical analysis of the data.
The positive expressiSCC. The expression levels of the 3 proteins can be used as important indicators for judging the clinical features and prognosis of patients with OSCC.
MMP-14, ING4 and HIF-1α are closely related to the progression of OSCC. Down-regulation of ING4 can promote up-regulation of MMP-14 and HIF-1α, and ultimately promote formation, growth, invasion and metastasis of OSCC. The expression levels of the 3 proteins can be used as important indicators for judging the clinical features and prognosis of patients with OSCC.
To explore the clinical characteristics of hematological diseases with oral presentation as the first manifestation, and to provide basis for early diagnosis of hematological diseases and prevention of missed diagnosis and misdiagnosis.
The clinical data of 500 patients with hematological diseases who were first diagnosed in department of stomatology in our hospital during the past five years were reviewed, and the diversity and distribution of oral manifestations of patients with hematological diseases were analyzed.
Oral manifestations of 500 patients with hematological diseases were mainly oral mucosa and gingival bleeding, gingival hyperplasia, oral mucosal ulcer, oral mucosal infection, oral and maxillofacial mass. Among them, the number of hematological diseases patients first diagnosed in the department of stomatology with the symptoms of oral and maxillofacial mass was the largest, accounting for 19.8%. Blood routine, coagulation mechanism and oral pathological biopsy were very important for preseases, combined with blood routine and coagulation mechanism examination, can preliminarily screen hematological diseases. Pathological examination of tumors in patients with oral and maxillofacial masses can be carried out. Diagnosis and differential diagnosis of hematological diseases can be made earlier in clinic, so as to avoid misdiagnosis and missed diagnosis. For patients with hematological diseases first diagnosed in the department of stomatology, the treatment of oral characterization mainly focuses on hematological diseases, supplemented by local symptomatic treatment of oral cavity.
To investigate the relationships among tongue volume, hyoid position, airway volume and maxillofacial form in paediatric patients with Class Ⅰ, Class Ⅱ and Class Ⅲ malocclusion.
Data of 112 children with malocclusion in the Department of Stomatology, Wuxi Children's Hospital from December 2015 to December 2018 were collected. The children were divided into three groups according to Angle's classification Class Ⅰ (n=42), Class Ⅱ (n=38) and Class Ⅲ (n=32). Tongue volume was evaluated by oral B-ultrasound, the hyoid position was obtained by lateral cephalogram, then the airway volume and maxillofacial form were evaluated by cone-beam CT (CBCT). Relationship among tongue volume, hyoid position, airway volume and maxillofacial form were analyzed. The data were processed by SPSS 20.0 software package.
The tongue volume of Class III was significantly larger than that of Class I and Class II (P<0.05); H-FH and H-MP of Class II were significantly larger than those of Class I and Class III, and H-VL was signifieve the best aesthetic and therapeutic effects.
To investigate the effect of pulp revascularization on the levels of CCL21 and IFN-γ-inducible protein 10(IP-10)in chronic periapical periodontitis.
One hundred patients with chronic periapical periodontitis treated from September 2018 to May 2019 were selected as the research subjects. They were divided into two groups by using random number table method. The patients in both groups were taken cone-beam CT(CBCT) film for filing before operation. Patients in the experimental group were treated by pulp revascularization, while patients in the control group were treated by apexification. The level of CCL21 and IP-10 was measured within 4 weeks. The results of operation, the ratio of crown to root and the thickness of root canal wall were analyzed. Statistical analysis of the data was conducted with SPSS 25.0 software package.
CCL21 and IP-10 levels of the two groups increased in the course of 1-3 weeks, but decreased after 4 weeks. CCL21 levels were significantly different at 2 weeks, 3 weeks and 4 weeks(P<0.https://www.selleckchem.com/products/gsk805.html
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