Gene Term Analysis Discloses Key Body's genes and also Signalings For this Analysis associated with Prostate type of cancer.

After adjusting for potential confounders, we did not find any association between dietary NEAC and stroke, either overall, or ischemic or hemorrhagic stroke (Ptrend > 0.05). CONCLUSION Higher dietary NEAC was not associated with any type of stroke in young and middle-aged Swedish women. OBJECTIVE Konjac oligo-glucomannan (KOG) is a non-digestible dietary fiber that is resistant to digestion and absorption in gastrointestinal (GI) tract. Thus, it might be used as an alternative management for constipation. The aim of this study was to evaluate the effects of KOG on gut motility and microbiota to relieve constipation in mice. METHODS Mice received Bifidobacterium animalis, lactulose, konjac glucomannan (KGM), or KOG for 14 d. Constipation was induced by 5 mg/kg loperamide days 12 through 14 in all groups except the control. Defecation frequency, small intestinal transit, and total gut transit time were indicated by counting the number of feces, and using charcoal meal and Evans blue as markers, respectively. Smooth muscle (SM) contraction and gut motility were evaluated by organ bath and GI motility monitor system. Gut microbiota were measured by fluorescence in situ hybridization technique. RESULTS KOG significantly (P less then 0.01) increased defecation frequency and small intestinal transit but decreased total gut transit time when compared with the constipation-without-treatment group. These results were similar to the effects of Bifidobacterium animalis, lactulose, and KGM. KOG ameliorated the effect of loperamide on contraction frequency of distal colonic circular SM. The motility patterns were changed in the KOG group from non-propagation to propagation contraction. KOG significantly inhibited the effects of loperamide on gut microbiota by increasing the numbers of Bifidobacterium spp. and decreasing the numbers of Clostridium spp. and Bacteroides spp. CONCLUSION These results suggest that KOG acts as a prebiotic and stimulant laxative for relief and prevention of constipation. OBJECTIVES Chumlea's formulas are a way of predicting height from knee height (KHt), including among individuals >60 y of age who cannot stand upright. However, the formulas were developed with white and African American people and have not yet been validated in native Africans >60 y of age. The aims of the study were to assess Chumlea's formulas in older people in central Africa and to propose a new validated formula for the same population. METHODS Height (MHt) and KHt were measured in a population of individuals >65 y of age from the Republic of Congo and the central African Republic. Predicted height (PHt) was calculated using Chumlea's formulas for the American black population (CBP) and for whites (CC). The percentages of accurate predictions (±5 cm) were compared between MHt and PHt. A new formula was estimated after randomization in a derivation sample (n = 877) and assessed for accuracy in a validation sample (n = 877). RESULTS The study included 1754 individuals. Prediction was accurate (±5 cm) in 66.8% and 63.2% of CBP and CC, respectively. Overestimation was as high as 24.1% and 29%, respectively. Because an overestimation is unacceptable in clinical practice and population surveys, a new formula was proposed height (cm) = 72.75 + (1.86 × KHt [cm]) - (0.13 × age [y]) + 3.41 × sex (0 women; 1 men). This new formula significantly increases accuracy (71.3%) and decreases overestimation (14.7%). The nutritional status based on body mass index did not differ with the MHt and the PHt by the new formula. CONCLUSION Chumlea's formulas provided a poor estimate of height in this population sample. The proposed formula more accurately estimates height in older native Africans. This formula should be tested in other sub-Saharan African countries to extend its use in clinical practice and in future studies. The aim of this study was to evaluate the effects of pegbovigrastim injection (Imrestor, Elanco Animal Health, Greenfield, IN) on production parameters and postpartum disease occurrence (retained placenta, metritis, displaced abomasum, and clinical mastitis) in dairy cows. Study cows (n = 270) were blocked by parity group (multiparous or primiparous) and randomly assigned to control (CON, n = 144) or pegbovigrastim treatment (IMR, n = 126). Ten ± 4 days before expected calving and again at calving, IMR cows received 2.7 mL of Imrestor and CON cows received 2.7 mL of 0.9 % saline. Milk yield, fat, protein, lactose, solids nonfat (SNF) percent, and somatic cell count (SCC), body condition, hygiene, and lameness were evaluated weekly. Animals were evaluated for metritis twice weekly through rectal temperature, palpation, and uterine discharge evaluation until 30 days in milk. Farm personnel recorded other postpartum diseases. The MIXED procedure of SAS was used to evaluate milk composition and milk yields were analyzed as repeated measures in time with block, treatment, calving month, and lactation week included in mixed models. The GLIMMIX procedure was used to evaluate mastitis and metritis occurrence. Variables entered a model if P ≤ 0.10 when screened individually. Variables with P ≤ 0.10 were kept in the final model. Milk yield, fat, protein, lactose, SNF, and log of SCC were not significantly affected by treatment. Clinical mastitis occurrence did not differ between treatments, but only 17 cases were detected. Compared to CON, IMR treated cows had increased clinical metritis incidence, and were 2.46 times more likely to develop the disease. No difference was observed on puerperal metritis ocurrence. Cows given pegbovigrastim injections had increased odds of developing clinical signs of metritis, but no negative effects on milk production or composition were observed. Published by Elsevier B.V.The English surveillance system for bovine brucellosis was evaluated. The confidence in detecting at least one infected herd in the local population (surveillance system sensitivity or SSe), and the confidence in freedom from disease (PFree) adjusted (PFreeAdj) for the probability of disease introduction from abroad by imported animals (PIntro), were estimated for quarterly surveillance periods of 2016; because dairy herds were tested quarterly on bulk tank milk (BTM) with an antibody indirect ELISA. A stochastic model was developed and six surveillance components (representing also the local population strata), were evaluated. SSR All English herds and their relative risk (RRs) of infection within each stratum were considered. The importance of each component was assessed using actual national data, which reflected non-random sampling. The contribution of the abortions testing was assessed with particular focus, because a decline in statutory submissions was observed in recent years. Beef herds without submissions (B-NoTest herds) at the laboratories were still considered as a population stratum, where infected cattle could be imported.SSR