Prior to the introduction of genetically modified (GM) insect-tolerant maize (Zea mays L.) in 1997, most part of the Argentinean production of this staple was concentrated in the humid and sub-humid temperate regions. Early spring sowings minimized the risk of water deficits around flowering and yield reduction due to pests. GM maize was the technology for optimizing sowing dates to synchronize critical periods for kernel set determination with those times of the year when water deficits are less probable, thus reducing large interannual variations in grain yield. Change in sowing date, however, did not start until 2009, after the occurrence of two successive dry phases of El Niño Southern Oscillation phenomenon. Land cropped to maize in Argentina expanded dramatically since then, particularly beyond the humid areas. Currently, maize is sown in an almost 50-50 % distribution between early and late sowings, including double cropping. Changes in agronomic practices such as sowing date and production areas can lead to changes in timing and intensity of water deficits along the maize growth cycle. This review provides an overview of new patterns of water deficit across humid, sub-humid and semi-arid mid-latitude environments of Argentina and their effects on grain yield and yield components.
Sleep problems are a public health burden and have adverse health consequences in older adults. Despite sleep being a shared biological process between couples, to date there have not been any studies that have assessed the association between retirement and sleep, in older couples. The objective of this study was to examine the impact of retirement on diagnosed sleep problems in older Dutch couples.
This study used data from two waves of the NIDI Pension Panel Study for older Dutch adults living with a partner (n= 3,726). Logistic regression models examined the strength of association between retirement and sleep problems, while accounting for the moderating role of relationship characteristics.
Retirement was associated with decreased odds of sleep problems at wave 2 (OR= 0.60, 95%CI=0.46-0.78). Lower relationship quality was associated with increased odds of sleep problems in the fully adjusted model (OR=1.81, 95%CI=1.32-2.49). Having a partner with sleep problems was associated with increased risk of sleep problems as well (OR=1.51, 95%CI=1.07-2.13). N-Ethylmaleimide in vivo There was evidence of effect modification by relationship quality (OR= 1.87, 95%CI =1.05-3.31).
Retirement and sleep do not occur in a social vacuum and have implications beyond the individual level. More research is therefore needed to understand the impact of sleep and its health consequences on older coupled workers. Such research may provide valuable insights for management and treatment of sleep problems and may have implications for public health of aging communities.
Retirement and sleep do not occur in a social vacuum and have implications beyond the individual level. More research is therefore needed to understand the impact of sleep and its health consequences on older coupled workers. Such research may provide valuable insights for management and treatment of sleep problems and may have implications for public health of aging communities.A 2.5 yr old female spayed domestic shorthair presented for acute tetraparesis, dull mentation, and fever. MRI and computed tomography identified a thin linear foreign body extending from the caudal nasopharynx through the atlanto-occipital joint and cervicomedullary junction. Signal changes within the musculature were consistent with myositis, edema, and abscessation. Inflammation and edema surrounded the foreign body, and a dorsal cervical myelopathy extended caudally to the level of C6. Computed tomography attenuation values of the foreign body were most consistent with plant material. Euthanasia was performed; postmortem dissection of the soft palate confirmed a plant stem with abscess.
Amnestic mild cognitive impairment (aMCI), a prodromal stage of Alzheimer's disease and other dementias, is characterized by episodic memory impairment. Recent evidence has shown inhibitory control deficits in aMCI, but the extent of these deficits across inhibitory domains (i.e., response inhibition and interference control) and aMCI subtypes (i.e., single- versus multiple-domain) remains unclear. Few studies have included response time intra-individual variability (RT IIV) in these efforts. The aim of this study was to compare response inhibition and interference control between aMCI subtypes using measures of accuracy, mean RT, and RT IIV.
We report data from 34 individuals with single-domain aMCI (sdaMCI, 66-86 years), 20 individuals with multiple-domain aMCI (mdaMCI, 68-88 years), and 52 healthy controls (64-88 years) who completed tasks of response inhibition (Go-NoGo) and interference control (Flanker). Group differences in accuracy, mean RT, and RT IIV were examined for both tasks.
Individuals with mdaMCI had higher RT IIV than the other groups on both tasks. In RT IIV, we observed an interference control deficit in mdaMCI and sdaMCI relative to healthy controls, a finding not observed through accuracy or mean RT.
RT IIV may detect subtle differences in inhibition deficits between aMCI subtypes that may not be evident with conventional behavioral measures. Findings support the supplementary use of RT IIV when assessing early executive function deficits.
RT IIV may detect subtle differences in inhibition deficits between aMCI subtypes that may not be evident with conventional behavioral measures. Findings support the supplementary use of RT IIV when assessing early executive function deficits.
Delayed Plasmodium falciparum parasite clearance has been associated with Single Nucleotide Polymorphisms (SNPs) in the kelch protein propeller domain (coded by pfk13 gene). SNPs in the Plasmodium falciparum multidrug resistance gene 1 (pfmdr1) are associated with multi-drug resistance including the combination artemether-lumefantrine. To our knowledge, this is the first work providing information on the prevalence of k13-propeller and pfmdr1 mutations from Sédhiou, a region in the south of Senegal.
147 dried blood spots on filter papers were collected from symptomatic patients attending a hospital located in Bounkiling City, Sédhiou Region, Southern Senegal. All samples were collected between 2015-2017 during the malaria transmission season. Specific regions of the gene pfk13 and pfmdr1 were analyzed using PCR amplification and Sanger sequencing.
The majority of parasites (92.9%) harboured the pfk13 wild type sequence and 6 samples harboured synonymous changes. Regarding pfmdr1, wild-type alleles represented the majority except at codon 184.N-Ethylmaleimide in vivo
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