upshot of different crosslinking agents on hybrid chitosan/collagen hydrogels for potential tissue engineering applications.Tissue technology ( TE ) demands scaffolds that have the necessary resistance to withstand the mechanical tensions once embeded in our body , as well as first-class biocompatibility . Hydrogels are asked as interesting materials for this purpose , especially those made from biopolymers . In this survey , the microstructure and rheologic performance , as well as functional and biological properties of chitosan and collagen hydrogels ( CH/CG ) crosslinked with different copulating factors , both born such as d-Fructose ( F ) , genipin ( G ) and transglutaminase ( T ) and semisynthetic , applying a combination of 1-ethyl-3- ( 3-dimethylaminopropyl ) carbodiimide hydrochloride with N-hydroxysuccinimide ( EDC/NHS ) will be evaluated . FTIR tests were transported out to determine if the proposed crosslinking responses for each crosslinking agent comed as expected , finding positive results in this aspect . Regarding the characterization of the holdings of each scheme , two main styles were observed , from which it could be established that crosslinking with G and EDC-NHS turned out to be more effective and good than with the other two crosslinking agents , producing pregnant advances with respect to the base CH/CG hydrogel .
In addition , in vitro tests demonstrated the potential covering in TE of these systems , particularly for those crosslinked with G , T and EDC-NHS.Reinforced hydrogel construction via organisation of alginate-chitosan double web with pH & salt-responsiveness and galvanizing conduction for soft actuators.Aiming at green and friendly environmental protection , polyvinyl alcohol/sodium alginate/chitosan ( PSCS ) double network hydrogel was successfully trained through diffusing the high molecular weighting chitosan into PVA/sodium alginate ( PS ) hydrogel without any other toxic reagents . The polyanion hydrogels could be significantly raised by immersing the polyanion hydrogel in high molecular weightiness chitosan solution without requiring specific structure . The PSCS hydrogel had a thick and rough surface construction with the pocket-sized porousness and larger crystallization degree compared with polyvinyl alcohol/sodium alginate hydrogels and polyvinyl alcohol/sodium alginate/Ca ( 2+ ) ( PSCa ) hydrogels . The PSCS hydrogel owned excellent hydrolysis resistance , the significant pH-sensitive and salt-sensitive swelling . In summation , the flexibility , youth 's modulus and mechanical dimensions of PSCS hydrogel can be conformed through the converting the content of sodium alginate PS , PSCa and PSCS had galvanic conductivity , and PSCS showed twice the conduction likened to PS hydrogel .
based on disputes of swelling ratio , a PSCS bilayer hydrogel was contrived and ushered first-class pH-driven distortion ability . The PSCS hydrogel is expected to extend the coating of hydrogels in preconditions asking stimulus reaction , and might serve as a bright intelligent actuators or soft robots.Synthesis and Characterization of Slow-Release Chitosan Oligosaccharide Pyridine Schiff Base Copper complex with fungicide Activity.Herein , a serial of chitosan oligosaccharide cop complexes altered with pyridine groups ( CPSx-Cu composites ) were successfully prepared via the Schiff base reaction and ion complexation response for slow-release fungicide . Selenium of the synthesized differentials were characterized via Fourier transform infrared spectrometry and ( 1 ) H and ( 13 ) C atomic magnetic sonorousness spectroscopy , and the unit configuration of the composite was figured using Gaussian software . The slow-release operation experimentation demonstrated that the cumulative copper ion release rate of CPSx-Cu complexes was drug-addicted on the type of substituents on the pyridine ring the in vitro and in vivo fungicidal actions of the CPSx-Cu complexes were inquired . At a concentration of 0 mg/mL , CPSx-Cu composites completely inhibited the maturation of Pythium vexans and Phytophthora capsici .
Clinical Nutrition indicated that CPSx-Cu complexes with slow-release ability exhibited better antifungal activeness than thiodiazole-copper and copper sulfate basic .Selenium
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